1. Mechanochemical Modeling of Bacterial Growth (Collaborator Sean X. Sun, JHU)
We
are studying E. Coli type gram negative bacterial growth from dynamical
system analysis motivated from mechanochemical framework.
E. Coli type bacterial show a fascinatingly robust
cylindrical structure. While growing in the longitudinal direction, the
growth in the radial direction is
allmost constant. This simple observation in microbiology is still
unexplained-our model is an attempt to provide a mathematical
explanation to this observation.
2.Biomechanics of Cancer Cell: We study mechanical phenotype changes dues to changes in invasiveness in cancer cell. For these, we use various
tool sets like, Atomic Force Microscopy, Micropipette Aspiration and
Traction Force Microscopy. We combine nanomechanical
probing techniques
with, optical imaging and mechanochemical computational modeling approach to understand biomechanics of cancer metastasis.
3. Mechanics of Brain in Computer aided Neurosurgery. 4. Modeling and Analysis of Microelectromechanical Cantilever sensor and actuator.