james gomes

Biography

I received my Bachelors degree in Chemical Engineering from Jadavpur University and my M.S. and Ph.D from Tulane University, New Orleans, USA. As a graduate student at Tulane, I received several awards including the prestigious Sigma Xi research award. I worked as Senior Process Engineer for Process Services Inc., Baton Rouge and as Executive Engineer for L&T, Powai, Mumbai, before joining IIT Delhi. My current research interest is in the area of Systems and Network Biology. We apply mathematical and computational methods to study disease networks, understand disease progression and determine new drug targets, followed by directed experiments. My group is interested in neurodegenerative diseases, virus-host interaction networks and malaria. The results of our work on Angiogenin gives a cohesive and comprehensive picture of the molecular origins of functional loss of all ALS associated ANG mutants. We recently created NeuroDNet, a database with interactive tools that enables the creation of interaction networks for neurodegenerative diseases under one portal for interrogation and analyses. It enables the construction and analysis of neurodegenerative diseases through protein interaction networks, regulatory networks and Boolean networks.