Redox sensitive self-assembling dipeptide for sustained intracellular drug delivery

['S Dhawan', 'S Ghosh', 'R Ravinder', 'SS Bais']

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Abstract

The rational design and synthesis of molecules with functional supramolecular assemblies continues to be a challenging endeavor. Self-assembled nano-and microstructures from natural building blocks are considered more appropriate for medical applications due to their biocompatible nature. We report for the first time a simple redox-responsive dipeptide that self-assembles to form vesicles in aqueous medium. The experimental results based on the control compound and all-atom molecular dynamics (MD) simulations support the

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