Dr. Kritika Singh
Project Associate
Kusuma School of Biological Sciences
Indian Institute of Technology, Delhi
Email: kritika.mini@gmail.com
Education: Ph.D. Biotechnology, Banaras Hindu University, India
Research project:
Investigation on CedA as primary protein responsible for coordination of bacterial chromosomal replication and cell division.
Based on previous studies conducted on CedA protein our main objective is to decipher the role of this DNA binding protein in Salmonella cell division and the cascade of events which follow up. This will involve use of biophysical and bioinformatic tools to understand the exact role of CedA in the process of cytokinesis. Also, we focuss to identify CedA binding proteins (CBPs) to gain more clues of CedA function
Selected publications:
K Singh, F Ahmad, VK Singh, K Kayastha, AM Kayastha. Purification, biochemical characterization and insilico analysis of alpha-amylase from Vicia faba. Journal of Molecular Liquids, 2017, 234, 133-141.
K Singh, M Shandilya, S Kundu, AM Kayastha. Heat, acid and chemically induced unfolding pathways, conformational stability and structure-function relationship in wheat ?-amylase. PLoS One, 2015, 10, e0129203.
K Singh, G Srivastava, M Talat, ON Srivastava, AM Kayastha. alpha-Amylase immobilization onto functionalized graphene nanosheets as scaffolds: Its characterization, kinetics and potential applications in starch based industries. Biochemistry and Biophysics Reports, 2015, 3, 18-25.
K Singh, AM Kayastha. alpha-Amylase from wheat (Triticum aestivum) seeds: Its purification, biochemical attributes and active site studies. Food Chemistry, 2014, 162, 1-9.
K Singh, AM Kayastha. Optimal immobilization of alpha-amylase from wheat (Triticum aestivum) onto DEAE-Cellulose using response surface methodology and its characterization. Journal of Molecular Catalysis B: Enzymatic, 2014, 104, 75-81.
C Singh, RK Rai, A Azim, N Sinha, A Ahmed, K Singh, AM Kayastha, AK Baronia, M Gurjar, B Poddar, RK Singh. Metabolic profiling of human lung injury by 1H high-resolution nuclear magnetic resonance spectroscopy of blood serum. Metabolomics, 2014, 11,166-174.
G Srivastava, K Singh, M Talat, ON Srivastava, AM Kayastha. Immobilization of fenugreek alpha-amylase onto functionalized graphene using response surface methodology. PLoS ONE, 2014, 9, e113408.
A Kumari, K Singh, AM Kayastha. alpha-Amylase: General properties, mechanism and biotechnological applications - a review. Current Biotechnology, 2012, 1, 98-107.
Workshop/Conference/Symposium attended:
Symposium on recent trends in Biophysics, Dept of Physics, Banaras Hindu University, Feb 13-15, 2010.
Workshop on emerging techniques of Biophysics, Dept of Physics, Banaras Hindu University, Feb 16, 2010.
Protein modeling and simulation: its applications in biological sciences, Centre of Bioinformatics, School of Biotechnology, Banaras Hindu University, Sept 15-16, 2009.
BRSI sixth International conference 2009 on 'Emerging Trends in Biotechnology' held at Banaras Hindu University, Dec 04-06, 2009.
Workshop on demonstration of Discovery studio 3.0, Centre of Bioinformatics, School of Biotechnology, Banaras Hindu University, Apr 20, 2011.
Awards/Fellowships/Grants:
Qualified National Eligibility Test (NET)-CSIR-JRF in Life Sciences (Dec. 2008).
Qualified Graduate Aptitude Test in Engineering (GATE) in Life Sciences (Feb. 2009) with 99.7 percentile.
Fellowship by Department of Biotechnology, India, to pursue Masters in Biotechnology (2007).
Previous Research Experience:
Research Associate (Nov. 2015- June 2017). Project topic "Computational screening and docking analysis of potential anti-hyperglycemic drug for Diabetes Type 2 management " under the guidance of Prof. O. N. Srivastava, Department of Physics, Institute of Science, Banaras Hindu University.
PhD (Sept. 2009- Jan. 2015). Thesis titled "Biochemical and Spectroscopic studies on alpha-Amylase from Triticum aestivum and its Applications" under the supervision of Prof. Arvind M. Kayastha, School of Biotechnology, Institute of Science, Banaras Hindu University.
