Research

Our current research initiatives are focused on:

  1. Development of engineered tissue constructs (e.g., cartilage and bone-like tissues) to replace diseased or injured organs,

  2. Establishment of simple in vitro disease model system (especially for arthritis, degenerative Intervertebral disc) by microfabricating tissue equivalents with precise spatiotemporal and cellular microenvironments, using cells and Textile polymer based constructs (made up of rapid prototyping, weaving, knitting, nonwoven, Fibre-hydrogel composite).
  3. To design some 'smart' textile architectures for medical applications, such as Hernia mesh, post-surgical adhesion preventive barrier, etc.





  • Tissue Engineering
    • Cartilage & Bone Tissue Engineering
    • Inter-vertebral disc regeneration
    • Establishment of in vitro disease model system
  • Medical Textiles
    • Wound dressings
    • Fibre-Hydrogel composite
    • Hernia Mesh
    • Sutures
  • Polymeric Nano-materials
    • Electrospinning
    • Rapid Prototyping for making novel scaffolds for Tissue engineering
    • Microfluidic chip-based Biosensors
  • Bioreactors
    • Dynamic culture condition for creating specific tissue microenvironment

Research Topics \ 3D Bioprinting

The ability to pattern functional materials in three dimensions has great potential to drive scientific and technological advances in the fields of chemistry, physics, biology, materials science, as well as several emerging areas, including photonics, microfluidics, printable electronics and biomaterials etc. Direct-write assembly allows one to design and rapidly fabricate materials in complex 3D shapes without the need for expensive tooling, dies, or lithographic masks. We are designing polymeric bioinks with tailored composition, viscosity to develop planar and complex 3D cellular architectures with feature sizes ranging from 3 μm to 300 μm.


Preparation of stem cell-laden micropatterned 3D constructs and multi-lineage differentiation


Pattern of cells for scalable control of engineered tissues


3D printed human skull using clinical imaging data

Publications

  • Acta Biomaterialia, 2015, 11, 233-246
  • Journal of Materials Chemistry B, 2015
  • Materials Technology: Advanced Biomaterials, 2014, 29 (B1) B10-B14
  • Biomacromolecules, 2013, 14, 311-321
  • Advanced Functional Materials, 2008, 18, 1883-1889