Research

Our current research initiatives are focused on:

1. Development of engineered tissue constructs (e.g., cartilage and bone-like tissues) to replace diseased or injured organs.


2. Establishment of simple in vitro disease model system (especially for arthritis, degenerative Intervertebral disc, skin, cornea) by engineering tissue equivalents with precise spatiotemporal and cellular microenvironments.


3. To design some 'smart' textile architectures for medical applications, such as wound dressing, Hernia mesh, post-surgical adhesion preventive barrier, etc.



We are particularly interested in understanding how cells sense information from materials (architectures, compositions, surface features and mechanical properties) and based on that information how cells self-assemble to create three-dimensional microenvironment, how fibrous ECM components can be organized within the tissue construct by simulating anatomical orientation, to correlate with its biomechanics.

• Tissue Engineering
  • Cartilage & Bone Tissue Engineering
  • Inter-vertebral disc regeneration
  • Establishment of in vitro disease model system
• Medical Textiles
• Wound dressings
• Fibre-Hydrogel composite
• Hernia Mesh
• Sutures
• Polymeric Nano-materials
  • Electrospinning
  • Rapid Prototyping for making novel scaffolds for Tissue engineering
  • Microfluidic chip-based Biosensors
• Bioreactors
  • Dynamic culture condition for creating specific tissue microenvironment

Research Topics
	3D bioprinting Engineering spatially-controlled cellular patterns with patient-specific geometries, preserving cell viability and functionality Read More
	Tissue engineering and Biomaterials Developing biomaterials having instructive chemical, architectural and mechanotransductional features Read More
	Controlling self-assembly of silk protein Directed assembly of silk-based biomaterials to achieve targeted functionality, immune response Read More
	In vitro disease model systems Establishment of relatively simple in vitro diseased tissue model serve as a foundation for our understanding about pathological conditions and explore therapeutic options Read More
	Medical Textiles   Read More
	Anti-cancer Therapeutics   Read More

To address those engrossing challenges, we are engaged in conducting research with interdisciplinary approaches of problem solving, which should benefit the society, rather than only generating decent impact publications.

Researchers in our laboratory come from various disciplines with backgrounds in textile technology, polymer sciences, biochemistry, chemical engineering, biotechnology, molecular and cellular biology. Clinicians and surgeons sometimes stop by.